Goals of the Human Genome Project

The Human Genome project was a project that has changed the face of medicine and the understanding of the human body and health. The project had several different goals and to help you understand why this project was such a big deal, Genolevures would like to share some of these goals with you.

The goals for this project was first put forward in 1988 by a committee of the US National Academy of Sciences. There were several five-year plans set out for completing the goals of the Human Genome Project. All the goals were completed within each of the given timeframes. The first goals were to develop physical and genetic maps. These goals make you wonder if services like Bozeman plastic surgery are going to be necessary in the future. In September 1994, the genetic map was completed and in October 1998 the physical map was completed. The other goals included:

1 - Goals of the Human Genome Project

DNA Sequencing – This goal was completed in April 2003 and aimed to sequence the human genetics. Scientists was successful in sequencing 99% of the human genetic makeup with an accuracy of 99.99%.

Map human sequence variation – Obviously, humans are different from each other and one of the goals was to determine the variance between different the genetics of different people. This goal was reached in February 2003 and 3.7 million human SNPs were successfully mapped.

Full-length human cDNAs – This goal has to do with gene identification and was completed in March 2003. Scientists successfully identified 15 000 full length human cDNAs.

Genomic-scale technologies – This goal was for functional analysis and was reached in sections across the span of 8 years. The first success was in 1994 when high throughput oligonucleotide synthesis DNA microarrays were done. Next were experiments with yeast genomes that led to more answers in 1996. A scale-up of two-hybrid system for protein-protein interaction was successfully developed from 1999 to 2002. The discoveries with yeast made a huge difference in how genetics are studied and yeast genomes are still used today to continue studies and research.

Complete genome sequences of model organisms – In order to do further research, the genomics of different species is needed. So, this goal involved the mapping of gene sequences for other organisms including. E. Coli, S. cerevisiae, and D. melanogaster. This goal was reached in April 2003 and would set the field for interspecies studies and understanding how humans and other species differ in genetic makeup.

2 - Goals of the Human Genome Project

The Human Genome Project may have been completed many years ago, but it and the knowledge it gave us will be used and researched for many years to come. Even with this knowledge, there is still so much that we don’t know and scientists are working hard on finding cures for diseases like cancer and how we can use our knowledge of genomics to prevent it or at least make it less severe.

Learn more about this project at the Human Genome Project website and read some of our earlier articles here and here.

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